I've been wrestling with Major Depression and anxiety for about five years now and I was on Remeron at one point for about a year. For me, it was very sedating which was actually what I needed because I had been in such a high anxiety state for so long(I had a high stress life and death job) that my body "recognized" this as normal and when therapy and biofeedback started working and I got more relaxed I got terrible panic attacks because my body no longer accecpted a more relaxed state as normal. The Remeron got me past that stage--then I changed medications to something less sedating, but I think I would have never gotten to be as recovered as I am now if I hadn't been on the Remeron for that period
